What does the Thyroglobulin Antibody - TGAB blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:
The Thyroglobulin Antibody (TGAB) test measures the level of antibodies produced against thyroglobulin, a protein made by the thyroid gland. This test is primarily used to: 1. Diagnose autoimmune thyroid conditions, particularly Hashimoto's thyroiditis 2. Monitor treatment progress in thyroid cancer patients 3. Assess the risk of developing thyroid dysfunction Elevated TGAB levels indicate that the immune system is attacking the thyroid gland, which can lead to thyroid dysfunction. The test is often performed alongside other thyroid function tests to provide a comprehensive evaluation of thyroid health.
A TGAB level below the lower range is generally not considered clinically significant. In fact, it’s normal and desirable to have low or undetectable levels of thyroglobulin antibodies. This typically indicates:
However, in thyroid cancer patients, very low TGAB levels may interfere with thyroglobulin measurements used for monitoring cancer recurrence.
Elevated TGAB levels (above 40 IU/mL) suggest the presence of autoimmune thyroid disease, most commonly Hashimoto’s thyroiditis. This indicates:
In thyroid cancer patients, high TGAB levels can interfere with thyroglobulin measurements, complicating cancer monitoring. Persistent elevation may also indicate an increased risk of thyroid cancer recurrence. Further evaluation and monitoring are typically recommended for individuals with high TGAB levels.