What does the Insulin-Like Growth Factor 1 - IGF-1 blood test mean? Get a free analysis of your blood test now. Here's what you get with our free analysis:
IGF-1 is a hormone similar in structure to insulin, playing a crucial role in growth and development. It's primarily produced in the liver in response to growth hormone (GH) stimulation. This test measures IGF-1 levels in the blood, which reflect average GH levels. It's used to: 1. Diagnose growth hormone deficiency or excess 2. Monitor treatment for growth disorders 3. Evaluate pituitary function 4. Screen for acromegaly or gigantism 5. Assess nutritional status IGF-1 levels vary with age, peaking during puberty and declining with age. Abnormal levels can indicate various endocrine disorders, affecting growth, metabolism, and overall health.
Low IGF-1 levels may indicate:
Low levels in children can lead to growth failure or short stature. In adults, it may cause decreased muscle mass, increased body fat, reduced bone density, and impaired cognitive function. Further testing, including growth hormone stimulation tests, may be necessary to determine the underlying cause.
Elevated IGF-1 levels may indicate:
High levels can lead to overgrowth of tissues, including enlarged hands, feet, and facial features. It may also increase the risk of certain cancers. In children, it can cause accelerated growth and early puberty. Additional tests, such as glucose suppression tests or imaging studies, may be required to confirm the diagnosis and identify the cause of elevated IGF-1 levels.